The ticket cost will again be around $10 USD. The journey from San Jose to Manuel Antonio/Quepos will take around 3.5 hours. From the Tracopa bus station, you will need to get the next bus headed to Manuel Antonio. You can get from one station to the next on foot, but the safest and easiest way would be to catch an Uber or a taxi - especially if you have luggage. However, the bus heading to Manuel Antonio and Quepos actually departs from a different bus station in San Jose - the Tracopa bus station. The journey to San Jose will take around 4.5 hours, and you will get off at the San Jose Terminal MEPE. You can find it by searching Terminal de MEPE in Google Maps.
In Puerto Viejo, you will need to catch the MEPE bus at the bus station in town. Better to keep any expensive or cherished items on you, in your carry-on, or within arm's length. Drivers will typically give you a luggage ticket that corresponds to your bag. When loading your luggage, make sure to give your bag to the driver only and make sure you see the bag go into the bus storage area. Bus travel is safe but we always recommend being cautious with your luggage. Tickets can normally be bought in advance and we recommend you do that whenever possible. Buses are typically air-conditioned and have assigned seats. When traveling from Puerto Viejo to Manuel Antonio, if you can catch 2 connecting buses without a big delay in between, the journey may not take much longer than traveling by car.
Traveling by bus in Costa Rica can be pretty straight-forward with a plan in place, it can be one of the best ways to travel the country. There are three ways to travel from Puerto Viejo to Manuel Antonio and Queposġ) By Bus (likely 9-10 hours, as you will need to catch a connecting bus in San Jose) (around $20 USD)